US Coast Pilot 6 provides supplemental navigation information for the Great Lakes system, including Lakes Ontario, Erie, Huron, Michigan, and Superior, their connecting waters, and the St. Lawrence River. It is intended to be used in conjunction with official navigational charts.

The United States Coast Pilot® is a series of nautical books published by the National Oceanic and Atmospheric Administration's (NOAA) Office of Coast Survey that cover a variety of information important to navigators of coastal and intracoastal waters and the Great Lakes. Issued in nine volumes, the Coast Pilots contain supplemental information that is difficult to portray on a nautical chart.

Topics include channel descriptions, anchorages, bridge and cable clearances, currents, tide and water levels, prominent features, pilotage, towage, weather, ice conditions, wharf descriptions, dangers, routes, traffic separation schemes, small-craft facilities, and Federal regulations applicable to navigation.

An amalgamated version of Navigation Rules is now included in the back of each Coast Pilot book.